Reaction #1747853

Reaction equation

sodium thiocyanate

Bromoacetophenone

Silane

→

Thiocyanato-acetophenone

Solvents

ethanol

Conditions

Workup

1. 1
   workup.ADDITIONThe glass surfaces thus treated
2. 2
   Washwere then washed five times
3. 3
   Otherfor 3 minutes
4. 4
   Otherat room temperature
5. 5
   WashAfter washing three times for three minutes each using respectively 30 mL of DCM at room temperature
6. 6
   Otherthe glass surfaces were dried
7. 7
   Otherstored at 4° C. until further use

Procedure

Bromoacetophenone-modified aminopropylsilylated glass surfaces (2.5×7.5 cm; Sigma, Silane-Prep™, S4651) (see Example 13) were coated with a 0.1M solution of sodium thiocyanate in ethanol and incubated for five hours at 50° C. The glass surfaces thus treated were then washed five times using respectively 30 mL of ethanol for 3 minutes each at room temperature. After washing three times for three minutes each using respectively 30 mL of DCM at room temperature, the glass surfaces were dried and stored at 4° C. until further use.

Source