Reaction #1726698

ord-89517c2aef894390b29f68af5590b7b2

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

4-Aryl-3-aminopyrazoles such as 4-phenyl-2H-pyrazol-3-ylamine may be prepared according to the procedures described in patent EP269,859 and illustrated in scheme 8, by reacting benzeneacetonitrile with orthoformic acid triethyl ester to give 3-oxo-2-phenyl-propionitrile which is reacted with hydrazine.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08110568B2uspto-grants-2012_02