Reaction #167607

ord-1e1dd58e4544478aa8617e820172e38d

Reaction equation

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
COc1cccc(OC)c1B(O)O
2,6-dimethoxyphenylboronic acid
→
COc1cccc(OC)c1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1
title compound
COc1cccc(OC)c1-c1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-[5-(2,6-dimethoxyphenyl)pyridin-3-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

Reactants

Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
product
Brc1cncc(N2CC3CC4CC2CN(C4)C3)c1
4-(5-Bromopyridin-3-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane
COc1cccc(OC)c1B(O)O
2,6-dimethoxyphenylboronic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared from the product of Example 65A and 2,6-dimethoxyphenylboronic acid according to General Method B: LC-MS Method D (ESI+) m/z 366.0 (M+H)+, retention time 1.34 minutes.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08846661B2uspto-grants-2014_09