Reaction #1605766

ord-49c629a992714aed9780acbfb44cb4cc

Reaction equation

COc1ccc(C(=O)O)cc1C
4-methoxy-3-methylbenzoic acid
COc1ccc2c(c1)CCC2N
5-methoxy-2,3-dihydro-1H-inden-1-amine
→
COc1ccc2c(c1)CCC2NC(=O)c1ccc(OC)c(C)c1
(R/S)-4-Methoxy-N-(5-methoxy-2,3-dihydro-1H-inden-1-yl)-3-methylbenzamide

Reactants

COc1ccc(C(=O)O)cc1C
4-methoxy-3-methylbenzoic acid
COc1ccc2c(c1)CCC2N
5-methoxy-2,3-dihydro-1H-inden-1-amine

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Prepared in a similar manner to example 4 using 4-methoxy-3-methylbenzoic acid and 5-methoxy-2,3-dihydro-1H-inden-1-amine (Example 121-2a)(47%). MS (M+Hs 312).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09072313B2uspto-grants-2015_07