Reaction #1593790

ord-38751b24b45d44c684ac000393dc795a

Reaction equation

CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1.Cl
bromhexine hydrochloride
OC[C@@H](O)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)CO
maltitol
O=C(O)c1ccccc1
benzoic acid
→
CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1
Bisolvon

Reactants

CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1.Cl
bromhexine hydrochloride
OC[C@@H](O)[C@@H](O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)CO
maltitol
O=C(O)c1ccccc1
benzoic acid

Reagents

None

Solvents

O
water

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

Composition: bromhexine hydrochloride (0.16 g/100 ml), maltitol liquid (50 g), benzoic acid (0.13 g/100 ml), flavourings, water.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09220693B2uspto-grants-2015_12