Reaction #1552054

Reaction equation

methyl-4-bromobenzoate

hydrazine monohydrate

→

white solid

Yield 67.0%

4-bromobenzohydrazide

Yield 67.0%

Solvents

ethanol

Conditions

Workup

1. 1
   Temperaturethe mixture was heated
2. 2
   workup.STIRRINGstirred at 78° C. for 5 hours
3. 3
   OtherA solid obtained
4. 4
   Washwashed with water
5. 5
   Filtrationcollected by suction filtration

Procedure

First, 3.0 g (13.9 mmol) of methyl-4-bromobenzoate was put in a 100-mL three-neck flask, 10 mL of ethanol was added therein, and the mixture was stirred. Thereafter, 4.0 mL of hydrazine monohydrate was added therein, and the mixture was heated and stirred at 78° C. for 5 hours. A solid obtained washed with water and collected by suction filtration; thus, 2.0 g of a white solid of objective 4-bromobenzohydrazide was obtained (yield: 67%).

Source