Reaction #1552043

ord-5457b3292eac4bc197a3beacfcc105ba

Reaction equation

C=CC(=O)NOC
N-methoxy-acrylamide
C=COC(=O)Cl
chloroformic acid vinyl ester
→
C=COC(=O)N(OC)C(=O)C=C
title compound
C=COC(=O)N(OC)C(=O)C=C
N-Methoxy-N-propenoylcarbamic acid vinyl ester

Reactants

C=CC(=O)NOC
N-methoxy-acrylamide
C=COC(=O)Cl
chloroformic acid vinyl ester

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    OtherPurification by column chromatography on silica gel (PE:EE=9:1)

Procedure

The synthesis was carried out analogously to synthesis example 8 using N-methoxy-acrylamide and chloroformic acid vinyl ester. Purification by column chromatography on silica gel (PE:EE=9:1) yielded 1.6 g (91% of th.) of the title compound as a colorless liquid.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08999323B2uspto-grants-2015_04