Reaction #1538536

Reaction equation

1-(3-phenylpropyl)-2-(1,3-dioxolan-2-yl)imidazole

benzyl bromide

→

3-benzyl-2-(1,3-dioxolan-2-yl)-1-(3-phenylpropyl)imidazolium bromide

Yield 87.0%

Conditions

Workup

1. 1
   OtherThe mixture was triturated with ethyl acetate
2. 2
   Otherdecanted
3. 3
   Otherdried

Procedure

A reaction mixture of 18 g (70 mmol) of 1-(3-phenylpropyl)-2-(1,3-dioxolan-2-yl)imidazole and 11.93 g (70 mmol) of benzyl bromide was stirred at room temperature for 8 h. The mixture was triturated with ethyl acetate, decanted and dried to afford 26.1 g (87%) of 3-benzyl-2-(1,3-dioxolan-2-yl)-1-(3-phenylpropyl)imidazolium bromide (Formula VI: A=1-(3-phenylpropyl)imidazole; Y=2-(1,3-dioxolan-2-yl; R1 =R6 =H; Z- =Br-).

Source