Reaction #1528403

Reaction equation

2-benzyloxy-4,6-dimethylpyridin-3-yl 3-fluoro-4-methylphenyl methanol

→

title compound

Yield 80.8%

3-(3-Fluoro-4-methylbenzyl)-4,6-dimethyl-1H-pyridin-2-one

Yield 80.8%

Solvents

ethanol

Conditions

Workup

1. 1
   OtherAfter the insoluble material was removed by filtration
2. 2
   Otherthe solvent of the filtrate was removed

Procedure

To a solution of 2-benzyloxy-4,6-dimethylpyridin-3-yl 3-fluoro-4-methylphenyl methanol (0.39 g) in ethanol (10 mL) was added a catalytic amount of palladium carbon powder, and the mixture was stirred at room temperature under a hydrogen atmosphere overnight. After the insoluble material was removed by filtration, the solvent of the filtrate was removed to give the title compound (0.22 g).

Source