Reaction #1470428

ord-52e67377daab48dead1aad684a960411

Reaction equation

CC1(C)CC(O)CC(C)(C)N1O
1-hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidine
CC(=O)O
acetic acid
→
CC(=O)[O-].CC1(C)CC(O)CC(C)(C)[NH+]1O
hydroxylamine
Yield 59.1%
CC(=O)[O-].CC1(C)CC(O)CC(C)(C)[NH+]1O
1-Hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidinium Acetate
Yield 59.1%

Reactants

CC1(C)CC(O)CC(C)(C)N1O
1-hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidine
CC(=O)O
acetic acid

Reagents

None

Solvents

CC(C)O
isopropanol

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

5.0 g (0.029 mol) 1-hydroxy-2,2,6,6-tetramethyl-4-hydroxypiperidine and 2.0 g (0.033 mol) acetic acid are recrystallized from 50 mL of isopropanol, yielding 4.0 g of the desired hydroxylamine salt as a white crystalline solid, mp 140-143° C.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US06254724B1uspto-grants-2001_07