Reaction #1470426

Reaction equation

1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

dimethylamine

→

title compound

Yield 82.8%

1-Oxyl-2,2,6,6-tetramethyl-4-(2-hydroxy-3-dimethylaminopropoxy)piperidine

Yield 82.8%

Solvents

water

Conditions

Workup

1. 1
   OtherWater is then removed by vacuum distillation

Procedure

A mixture of 10.0 g (0.044 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 10 mL of 40% (ca. 0.091 mol) of dimethylamine (w/w) is dissolved in 100 mL of water and then stirred for 16 hours at ambient temperature. Water is then removed by vacuum distillation to leave 10 g of the title compound as a red oil.

Source