Reaction #1350566

Reaction equation

( 1 )

Cyanuric chloride

Potassium hydrogen carbonate

propylamine

Cyanuric chloride

→

4,6-dichloro-2-propylamino-1,3,5-triazine

Solvents

water

acetone

Conditions

Workup

1. 1
   Temperaturecooled in an ice/acetone bath
2. 2
   Temperaturewhile maintaining the temperature below 0° C
3. 3
   workup.STIRRINGstirred for 1 hour at room temperature
4. 4
   OtherThe acetone was evaporated off under reduced pressure
5. 5
   workup.ADDITIONthe residue (300 ml) was poured into water (11)
6. 6
   FiltrationThe resulting white solid was filtered
7. 7
   Washwashed with water
8. 8
   Otherdried under vacuum

Procedure

Cyanuric chloride (1) (36.9 g, 0.2 mole) was dissolved in acetone (600 ml) and cooled in an ice/acetone bath. Potassium hydrogen carbonate (25.03 g,0.25 mole) was dissolved in water (150 ml) with propylamine (11.82 g, 0.2 mole) and added dropwise to the solution of (1) while maintaining the temperature below 0° C. The mixture was stirred for 1 hour at 0° C. and then stirred for 1 hour at room temperature. The acetone was evaporated off under reduced pressure and the residue (300 ml) was poured into water (11). The resulting white solid was filtered, washed with water and dried under vacuum.

Source