Reaction #1265417

ord-d17cf91fdd214bc996f2c2341a862af2

Reaction equation

c1ccc2c(c1)CCNC2
3,4-dihydro-1H-isoquinoline
O=C(Cl)CCCCl
4-chlorobutanoyl chloride
→
O=C(CCCCl)N1CCc2ccccc2C1
4-Chloro-1-(3,4-dihydro-1H-isoquinolin-2-yl)butan-1-one

Reactants

c1ccc2c(c1)CCNC2
3,4-dihydro-1H-isoquinoline
O=C(Cl)CCCCl
4-chlorobutanoyl chloride

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

from 3,4-dihydro-1H-isoquinoline and 4-chlorobutanoyl chloride

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07276508B2uspto-grants-2007_10