Reaction #1265408

Reaction equation

3,4-dimethoxyphenylglyoxal

methanol

2-amino-4-ethoxy-7-(3,4-dimethoxyphenyl) pteridine

→

2-amino-4-methoxy-7-(3,4-dimethoxyphenyl) Pteridine

Solvents

isopropanol

Conditions

Procedure

The sequence of reactions described in examples 106 to 110 was followed, however starting from 3,4-dimethoxyphenylglyoxal instead of 4-methoxyphenylglyoxal in the first step, and from methanol instead if isopropanol in the last step. This provided 2-amino-4-ethoxy-7-(3,4-dimethoxyphenyl) pteridine, a compound which was further characterized by its mass spectrum: 314 ([M+H]+, 100), 300 ([M+H-methane]+, 20).

Source