Reaction #1265369
ord-9ddddc4f8b124809a4e0345279e96eed
Reaction equation
3,4,5-trimethoxyaniline
3,5-dicarboxy-aniline
→
2,3,4-trimethoxycyclohexylamine
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
3,4,5-trimethoxyaniline was hydrogenated via the procedure given for 3,5-dicarboxy-aniline to provide 2,3,4-trimethoxycyclohexylamine which was coupled to the C-terminal valine in the standard way.