Reaction #1256745

ord-844775fd74eb46848986d4a150b8bd07

Reaction equation

CC(C)C[SiH](C(C)C)C(C)C
Compound 40a
CC(C)C[SiH](C(C)C)C(C)C
Isobutyldiisopropylsilane
CC(C)[SiH](Cl)C(C)C
diisopropylchlorosilane
→
CC(C)[SiH](C(C)C)C1CC1
Compound 44a
CC(C)[SiH](C(C)C)C1CC1
Cyclopropyldiisopropylsilane

Reactants

CC(C)C[SiH](C(C)C)C(C)C
Compound 40a
CC(C)C[SiH](C(C)C)C(C)C
Isobutyldiisopropylsilane
CC(C)[SiH](Cl)C(C)C
diisopropylchlorosilane

Reagents

None

Solvents

—
cyclopropylmagnesium bromide THF

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The procedure of synthesizing Compound 40a was repeated, except that diisopropylchlorosilane (4.10 mL, 96.0 mmol) and cyclopropylmagnesium bromide THF solution (1.0M, 100 mL) were employed, whereby the Compound 44a was obtained as a colorless liquid (boiling point; 35 mmHg, 86 to 89° C. fraction, 1.84 g, 50%).

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07825103B2uspto-grants-2010_11