Reaction #1240

ord-3150c5b19251400f94abae6bc2510c0b

Reaction equation

CC(C)(C)[Si](C)(C)Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene
OBO
boronic acid
→
CC(C)(C)[Si](C)(C)Oc1cc2ccc(B(O)O)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-naphthylboronic acid

Reactants

CC(C)(C)[Si](C)(C)Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene
OBO
boronic acid

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherwere obtained

Procedure

Following the basic procedure of Example 7(e), beginning with 11.9 g (25.4 mmol) of 7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene, 8.37 g (75%) of the expected boronic acid of melting point 221°-222° C. were obtained.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05723499uspto-grants-1998_03