Reaction #1231
ord-9a85735f44d44b4dad4458afbbf407f8
Reaction equation
methyl 4-[7-(1-adamantyl)-6-hydroxy-2-naphthyl]benzoate
methoxyethoxymethyl chloride
→
expected compound
Yield 55.0%
methyl 4-[7-(1-adamantyl)-6-methoxyethoxymethoxy-2-naphthyl]benzoate
Yield 55.0%
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
Following the basic procedure of Example 12, by reacting 980 mg (2.4 mmol) of methyl 4-[7-(1-adamantyl)-6-hydroxy-2-naphthyl]benzoate with 330 μl (28.6 mmol) of methoxyethoxymethyl chloride, 650 mg (55%) of the expected compound were obtained in the form of an oil.