Reaction #1212

Reaction equation

cyclohexadecanolide

ethanolamine

methyl 16-(2-tetrahydropyranyloxy)hexadecanate

diethanolamine

→

title compound

16-(2-hydroxyethylamino)-1-(2-tetrahydropyranyloxy)hexadecane

Conditions

Workup

1. 1
   Otherrespectively, in Preparation Example 37

Procedure

A reaction was conducted in the same manner as in Preparation Example 37 except that ethanolamine and methyl 16-(2-tetrahydropyranyloxy)hexadecanate were used in place of diethanolamine and cyclohexadecanolide, respectively, in Preparation Example 37, thereby obtaining the title compound (IId-4).

Source