Reaction #1178462
ord-0eb7448356d8486296e793d9e104e226
Reaction equation
2-amino-benzothiazol-5-ol
2-amino-benzothiazol-7-ol
→
3-methoxyaniline
ammoniumthiocyanate
Reagents
None
Conditions
Detailed conditions
See reaction.notes.procedure_details.
Procedure
The two derivatives that are not commercially available (2-amino-benzothiazol-5-ol and 2-amino-benzothiazol-7-ol) can be obtained by cyclization of 3-methoxyaniline with ammoniumthiocyanate followed by demethylation with boron tribromide as outlined in the scheme below: