Reaction #1178388

ord-9b6ecdf8dfcc434aa8562bd50920dea3

Reaction equation

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
mannitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
Yield 119.7%

Reactants

Reagents

None

Solvents

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Workup

  1. 1
    Otherthe resulting wet granules were dried

Procedure

The procedure of Example 1 was repeated except that 300 mg of mannitol was dissolved in a mixture of 10 mg of water and 10 mg of ethanol, the solution was subjected to wet granulation, and the resulting wet granules were dried and used as the sugar alcohol, not 300 mg of xylitol, to obtain an inventive rapidly disintegrating formulation tablet.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08127516B2uspto-grants-2012_03