Reaction #1144442

Reaction equation

bupivacaine

bupivacaine

bupivacaine

epinephrine

→

Ephedrine

Conditions

Workup

1. 1
   Otherare prepared, in a percent loading of about 0.05 percent, by weight
2. 2
   workup.ADDITIONIn addition, microspheres containing

Procedure

Microspheres containing bupivacaine loaded to about 75 percent by weight with bupivacaine are prepared, in a percent loading of about 0.05 percent, by weight, using the methods described in EXAMPLES 1-3 or EXAMPLES 4-9, above. In addition, microspheres containing added epinephrine, in a percent loadings of 0.001 percent, 0.05 percent and 1 percent, without bupivacaine, are also prepared according to EXAMPLES 1-3 or EXAMPLES 4-9, above.

Source