Reaction #1135798

Reaction equation

1-chloro-2-methyl-3-methoxycarbonylaminobenzene

phosphorus pentachloride

→

1-chloro-3-isocyanato-2-methylbenzene

Solvents

chlorobenzene

Conditions

Workup

1. 1
   Temperaturewith heating
2. 2
   Temperatureunder reflux for one hour
3. 3
   OtherThe reaction mixtures
4. 4
   Concentrationwere concentrated under reduced pressure

Procedure

A mixture of the above-mentioned 1-chloro-2-methyl-3-methoxycarbonylaminobenzene 5.80 g, phosphorus pentachloride 7.53 g and chlorobenzene 50 mL was stirred with heating under reflux for one hour. The reaction mixtures were concentrated under reduced pressure to give 1-chloro-3-isocyanato-2-methylbenzene.

Source