Reaction #11356

Reaction equation

2-hydroxybenzonitrile

potassium carbonate

ethyl bromide

→

2-Ethoxybenzonitrile

Solvents

acetone

Conditions

Workup

1. 1
   FiltrationThe solid is filtered off
2. 2
   Otherthe solvent is removed under reduced pressure
3. 3
   workup.DISTILLATIONthe residue is distilled under reduced pressure

Procedure

25 g (210 mmol) of 2-hydroxybenzonitrile, 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide are refluxed in 500 ml of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure. This gives 30.0 g (97%) of a colorless liquid.

Source