Reaction #1006027

ord-dc5dd599e77e4860b04fe4495bdc94fd

Reaction equation

NCc1c(F)cccc1Cl
(2-chloro-6-fluorophenyl)methanamine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
O=C(NCc1c(F)cccc1Cl)c1cn2cc(Br)ccc2n1
title compound
O=C(NCc1c(F)cccc1Cl)c1cn2cc(Br)ccc2n1
6-Bromo-N-(2-chloro-6-fluorobenzyl)imidazo[1,2-a]pyridine-2-carboxamide

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2-chloro-6-fluorophenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09271969B2uspto-grants-2016_03