Reaction #1006025

ord-dc48e0c038c449f69c3d8ad15acd07d0

Reaction equation

NCc1ccc(Oc2ccc(F)cc2)cc1
(4-(4-fluorophenoxy)phenyl)methanamine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
→
O=C(NCc1ccc(Oc2ccc(F)cc2)cc1)c1cn2cc(Br)ccc2n1
title compound
O=C(NCc1ccc(Oc2ccc(F)cc2)cc1)c1cn2cc(Br)ccc2n1
6-Bromo-N-(4-(4-fluorophenoxy)benzyl)imidazo[1,2-a]pyridine-2-carboxamide

Reactants

—
Intermediate I
NCc1ccc(Oc2ccc(F)cc2)cc1
(4-(4-fluorophenoxy)phenyl)methanamine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (4-(4-fluorophenoxy)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09271969B2uspto-grants-2016_03