Reaction #1006021

ord-32258fe0aded4d7d8dd22a350a77f1fa

Reaction equation

CC(C)(N)c1ccc(F)cc1
2-(4-fluorophenyl)propan-2-amine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
→
CC(C)(NC(=O)c1cn2cc(Br)ccc2n1)c1ccc(F)cc1
title compound
CC(C)(NC(=O)c1cn2cc(Br)ccc2n1)c1ccc(F)cc1
6-Bromo-N-(2-(4-fluorophenyl)propan-2-yl)imidazo[1,2-a]pyridine-2-carboxamide

Reactants

—
Intermediate I
CC(C)(N)c1ccc(F)cc1
2-(4-fluorophenyl)propan-2-amine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Reagents

None

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 2-(4-fluorophenyl)propan-2-amine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09271969B2uspto-grants-2016_03