Reaction #1006012

ord-f96621dfabe548748627defbc3212a48

Reaction equation

NCc1ccc(C(F)(F)F)c(F)c1
(3-fluoro-4-(trifluoromethyl)phenyl)methanamine
CCOC(=O)c1cn2cc(Br)ccc2n1
ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate
O=C(NCc1ccc(C(F)(F)F)c(F)c1)c1cn2cc(Br)ccc2n1
title compound
O=C(NCc1ccc(C(F)(F)F)c(F)c1)c1cn2cc(Br)ccc2n1
6-Bromo-N-(3-fluoro-4-(trifluoromethyl)benzyl)imidazo[1,2-a]pyridine-2-carboxamide

Conditions

Detailed conditions
See reaction.notes.procedure_details.

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (3-fluoro-4-(trifluoromethyl)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Source

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09271969B2uspto-grants-2016_03