(+)-tramadol

CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1
Reaction #6661
O-desmethyl tramadol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_08
CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1
Reaction #216583
O-desmethyl tramadol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1995_11
CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1
Reaction #526998
O-desmethyl tramadol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1996_05
COc1cccc(C2(O)CCCCC2CN(C)C)c1
Reaction #1079950
Tramadol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2002_10
—
Reaction #1140126
solid
Yield 53.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_07
COc1ccc2cc([C@@H](C)C(=O)O)ccc2c1.COc1cccc([C@@]2(O)CCCC[C@@H]2CN(C)C)c1
Reaction #1140127
(+)-tramadol (R)-naproxen
Yield 61.5%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_07
CN(C)C[C@H]1CCCC[C@]1(O)c1cccc(O)c1
Reaction #1829210
O-desmethyl tramadol
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1994_08