Cs2CO3

CCOC(=O)c1cnc2cc(OCC)c(N3CCN(C(C)C)CC3)cc2c1Nc1ccc(F)cc1F
Reaction #97
Yield 65.4%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #98
Yield 57.5%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #99
Yield 65.4%750 AstraZeneca ELN dataset
COC(=O)c1cc2c(ncn2C)c(F)c1Nc1ccccc1
Reaction #100
Yield 75.1%750 AstraZeneca ELN dataset
Cc1ccc(Oc2ccnc(Nc3ccc(S(N)(=O)=O)cc3)c2)c(C)n1
Reaction #101
Yield 46.3%750 AstraZeneca ELN dataset
Cc1ccc(Oc2ccnc(Nc3ccc(S(N)(=O)=O)cc3)c2)c(C)n1
Reaction #102
Yield 76.0%750 AstraZeneca ELN dataset
Cc1ccc(Oc2ccnc(Nc3ccc(S(N)(=O)=O)cc3)c2)c(C)n1
Reaction #103
Yield 40.9%750 AstraZeneca ELN dataset
Cc1ccc(Oc2ccnc(Nc3ccc(S(N)(=O)=O)cc3)c2)c(C)n1
Reaction #104
Yield 62.4%750 AstraZeneca ELN dataset
CC(=O)N1CCN(c2cncc(Br)c2)CC1
Reaction #105
Yield 31.8%750 AstraZeneca ELN dataset
CN1Cc2ccc(Nc3ccc(-n4ccnc4)cc3)nc2OC(c2ccccc2)C1
Reaction #106
Yield 41.5%750 AstraZeneca ELN dataset
COc1cc(Nc2ccc3c(n2)OC(c2cccnc2)CN(C(C)=O)C3)ccc1-n1cnc(C)c1
Reaction #107
Yield 35.1%750 AstraZeneca ELN dataset
COc1cc(Nc2ccc3c(n2)OC(c2cccnc2)CN(C)C3)ccc1-n1cnc(C)c1
Reaction #108
Yield 27.8%750 AstraZeneca ELN dataset
CC(C)(C)OC(=O)Nc1cc(F)ccn1
Reaction #109
Yield 19.5%750 AstraZeneca ELN dataset
CC(=O)Nc1cc(Nc2c(Cl)ccc3c2OCO3)ccn1
Reaction #117
Yield 83.1%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #118
Yield 42.5%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #119
Yield 63.3%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #120
Yield 49.4%750 AstraZeneca ELN dataset
CN1CCc2cccc(Nc3cc(Cl)ncc3Cl)c2C1=O
Reaction #121
Yield 59.5%750 AstraZeneca ELN dataset
CONC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #122
Yield 39.1%750 AstraZeneca ELN dataset
CONC(=O)c1ccccc1Nc1cc(Cl)ncc1Cl
Reaction #123
Yield 69.2%750 AstraZeneca ELN dataset
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