Doxorubicin hydrochloride

CCOC(=O)C(CC(=O)NC(C)C)CC1(C(=O)N[C@H]2CCc3ccccc3N(CC(=O)OC(C)(C)C)C2=O)CCCC1
Reaction #60628
Ethyl 2-{[(3S)-1-({[1-(2-tert.butoxy-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}carbonyl)cyclopentyl]methyl}-4-(isopropylamino)-4-oxobutyrate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2008_09
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #637507
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_05
CCOC(=O)C(CC(=O)NC(C)C)CC1(C(=O)N[C@H]2CCc3ccccc3N(CC(=O)OC(C)(C)C)C2=O)CCCC1
Reaction #942739
Ethyl 2-{[(3S)-1-({[1-(2-tert. butoxy-2-oxoethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino}carbonyl)cyclopentyl]methyl}-4-(isopropylamino)-4-oxobutyrate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2007_08
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.O=S(=O)([O-])[O-]
Reaction #961268
doxorubicin sulfate
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2015_03
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #979022
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_02
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #983936
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2005_07
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1.O=P1(N(CCCl)CCCl)NCCCO1
Reaction #991793
Cyclophosphamide Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1983_12
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1016557
compound ( 1 )
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_03
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1055631
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2007_12
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1096641
title compound
Yield 317.1%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2011_07
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1121558
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1994_05
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1121559
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1994_05
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1121560
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-1994_05
COC(=O)[C@H]1O[C@@H](Oc2ccc(COC(=O)N3CCOC3CCCNC3CC(OC4C[C@](O)(C(=O)CO)Cc5c(O)c6c(c(O)c54)C(=O)c4c(OC)cccc4C6=O)OC(C)C3O)cc2NC(=O)CCNC(=O)OCC2c3ccccc3-c3ccccc32)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O
Reaction #1132461
16
Yield 41.0%DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2013_10
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1140497
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2016_07
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1145700
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2003_02
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1255288
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2003_09
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1255289
doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2003_09
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1331369
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2006_10
COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)(C(=O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1
Reaction #1366160
Doxorubicin
DOI: 10.6084/m9.figshare.5104873.v1uspto-grants-2002_09
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