Reaktion #9963

Reaktionsgleichung

thionyl chloride

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoic acid

→

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoyl Chloride

Lösungsmittel

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturcooled
2. 2
   Einengenconcentrated under reduced pressure, co-evaporated with ethyl acetate (2×100 mL)
3. 3
   Sonstigethe oil so obtained

Vorschrift

2-[(4-Dodecyloxyphenyl)sulfonyl]butanoic acid (19.5 g, 47.33 mMole) was suspended in ethyl acetate (150 mL) to which was added several drops of dimethylformamide and thionyl chloride (14.4 mL, 119 mMole). The mixture was heated at 70° C. for 1.5 hours, cooled, concentrated under reduced pressure, co-evaporated with ethyl acetate (2×100 mL) and the oil so obtained used as such in the next step of the reaction sequence.

Quelle