Reaktion #992700

Reaktionsgleichung

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

title product

3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide

→

title compound

2-amino-3-methyl-N-(1-methylethyl)benzeneacetamide

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas placed under a balloon of nitrogen overnight
2. 2
   FiltrationThen the reaction mixture was filtered through Celite® diatomaceous filter aid
3. 3
   SonstigeThe solvent was removed with a rotary evaporator

Vorschrift

To 3-methyl-N-(1-methylethyl)-2-nitrobenzeneacetamide (i.e. the title product of Step A) (0.40 g, 1.7 mmol) and 10% palladium on carbon (0.13 g) was added 20 mL of ethanol. The reaction mixture was placed under a balloon of nitrogen overnight. Then the reaction mixture was filtered through Celite® diatomaceous filter aid. The solvent was removed with a rotary evaporator to afford the title compound as a tan solid (0.29 g).

Quelle