Reaktion #992388

Reaktionsgleichung

Thionyl chloride

1-[2-(6-methyl-2-naphthyl)-2-hydroxyethyl]imidazole

→

1-[2-(6-methyl-2-naphthyl)-2-chloroethyl]imidazole hydrochloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThereafter, the solution is evaporated to dryness
2. 2
   workup.ADDITIONthe residue is treated with ethyl acetate
3. 3
   Filtrationfiltered

Vorschrift

Thionyl chloride (5 ml.) and 2.0 g. of 1-[2-(6-methyl-2-naphthyl)-2-hydroxyethyl]imidazole are stirred at room temperature for about 20 minutes. Thereafter, the solution is evaporated to dryness and the residue is treated with ethyl acetate and filtered to yield 1-[2-(6-methyl-2-naphthyl)-2-chloroethyl]imidazole hydrochloride.

Quelle