Reaktion #991145

Reaktionsgleichung

water

guaiacol sodium salt

1-phenylallyl-chloride

→

3-(2-methoxy-phenoxy)-3-phenyl-propylene

Ausbeute 99.2%

Lösungsmittel

dimethylformamide

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted with ethyl ether
2. 2
   Sonstigefollowed by chromatographic separation

Vorschrift

To a solution of 5 g of guaiacol sodium salt in 60 ml of dimethylformamide, 1-phenylallyl-chloride (5.22 g) (J.C.S. 1959, p. 2720) was added under a nitrogen atmosphere. The whole was stirred for 4 hours at room temperature and for two hours at 50° C., poured into water and extracted with ethyl ether. After standard working up, followed by chromatographic separation, 3-(2-methoxy-phenoxy)-3-phenyl-propylene (8.1 g; 98%) was obtained.

Quelle