Reaktion #985329

Reaktionsgleichung

6-piperazinyl-1H-pyrrolo[2,3-b]pyridine

6-(4-cyclopentyl-piperazin-1-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid hydrochloride

6-(4-Cyclopentyl-piperazin-1-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid hydrochloride

→

[6-(4-Cyclopentyl-piperazin-1-yl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-piperidin-1-yl-methanone

Reaktionsbedingungen

Vorschrift

According to the procedure described for the synthesis of Example 1 further 6-piperazinyl-1H-pyrrolo[2,3-b]pyridine derivatives have been synthesized from 6-(4-cyclopentyl-piperazin-1-yl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid hydrochloride (as prepared in step 2) and the respective amine mentioned in table 1. The examples are compiled in table 1 and comprise Example 2 to Example 20.

Quelle