Reaktion #985262

Reaktionsgleichung

2-(4-nitrophenyl)benzothiazole

tin (II) chloride dihydrate

→

2-(4-Aminophenyl)benzothiazole

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed under N2 for 4 hrs
2. 2
   SonstigeAfter removing ethanol
3. 3
   Sonstigeby vacuum evaporation
4. 4
   workup.DISSOLUTIONThe residue was dissolved into ethyl acetate (20 ml)
5. 5
   Waschenwashed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml)
6. 6
   Sonstigedried
7. 7
   Sonstigeevaporated to dryness to givelo2 mg (97%) of the product

Vorschrift

A mixture of 2-(4-nitrophenyl)benzothiazole (105 mg, 0.40 mmol) and tin (II) chloride dihydrate (205 mg, 0.91 mmol) in ethanol (20 mL) was refluxed under N2 for 4 hrs. After removing ethanol by vacuum evaporation. The residue was dissolved into ethyl acetate (20 ml), and washed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml), dried and evaporated to dryness to givelo2 mg (97%) of the product

Quelle