Reaktion #985257

Reaktionsgleichung

2-(4-nitrophenylethenyl)benthiazole

Trans-2-(4-Nitrophenylethenyl)benzothiazole

tin (II) chloride dihydrate

→

product 12

Ausbeute 9.3%

2-(4-Aminophenylethenyl)benzothiazole

Ausbeute 9.3%

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed under N2 for 4 hrs
2. 2
   SonstigeEthanol was removed by vacuum evaporation
3. 3
   workup.DISSOLUTIONThe residue was dissolved into ethyl acetate (20 ml)
4. 4
   Waschenwashed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml)
5. 5
   Trocknendried over MgSO4
6. 6
   SonstigeEvaporation to dryness

Vorschrift

A mixture of 2-(4-nitrophenylethenyl)benthiazole 11 (500 mg, 1.7 mmol) and tin (II) chloride dihydrate (1.18 g, 5.2 mmol) in anhydrous ethanol (20 ml) was refluxed under N2 for 4 hrs. Ethanol was removed by vacuum evaporation. The residue was dissolved into ethyl acetate (20 ml), washed with NaOH solution (1 N, 3×20 ml) and water (3×20 ml), and dried over MgSO4. Evaporation to dryness gave 40 mg (8.0%) of product 12.

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