Reaktion #981389

ord-868c5e9586fe4bcb973605cfdde217e1

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    Extraktionextract with ether
  2. 2
    SonstigeEvaporate to dryness and chromatograph over silica gel with benzene as the eluting solvent

Vorschrift

Mix 0.415 gm of potassium tert-butoxide, 5 ml of methanol and 5 ml of dimethylformamide and add the mixture to a solution of 1.07 gm of methyl 6,11-dihydro-11-chlorodibenz[b,e]oxepin-2-carboxylate in 40 ml of dimethylformamide. Stir at room temperature for 3 days. Dilute with water and extract with ether. Evaporate to dryness and chromatograph over silica gel with benzene as the eluting solvent to obtain the title product.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04282365uspto-grants-1981_08