Reaktion #981147

Reaktionsgleichung

diethyl ether

dimethoxyphosphoryl isocyanate

2-cyanoaziridine

diethyl ether

→

1-N-Dimethoxyphosphoryl-carbamoyl-2-cyanoaziridine

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe precipitated crystals are filtered off with suction
2. 2
   Waschenwashed with diethyl ether

Vorschrift

A solution of 3.6 g. dimethoxyphosphoryl isocyanate in 18 ml. anhydrous diethyl ether is added dropwise at 5°-10° C. to a solution of 1.62 g. 2-cyanoaziridine in 36 ml. anhydrous diethyl ether. After stirring for 2 hours in an ice bath, the reaction mixture is allowed to warm to ambient temperature. The precipitated crystals are filtered off with suction and washed with diethyl ether. There is thus obtained 1.85 g. 1-N-dimethoxyphosphoryl-carbamoyl-2-cyanoaziridine; m.p. 72°-76° C. (decomp.).

Quelle