Reaktion #9760

ord-22738bd0ee6c4942bad63a5abef978f4

Reaktionsgleichung

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
intermediate 44
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate
CNC1CCCCC1
N-methylcyclohexylamine
→
CN(Cc1oc(-c2ccc(C(F)(F)F)cc2)cc1CO)C1CCCCC1
{2-{[cyclohexyl(methyl)amino]methyl}-5-[4-(trifluoromethyl)phenyl]-3-furyl}methanol

Edukte

COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
intermediate 44
COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)oc1CBr
Methyl 2-bromomethyl-5-[4-(trifluoromethyl)phenyl]-3-furoate
CNC1CCCCC1
N-methylcyclohexylamine

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared using intermediate 44 and N-methylcyclohexylamine.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US07091237B2uspto-grants-2006_08