Reaktion #9725

Reaktionsgleichung

ethyl 3-[4-(benzyloxy)-2-methylphenyl]prop-2-enoate

intermediate 11

ethyl 3-[4-(benzyloxy)-2-methylphenyl]prop-2-enoate

→

title compound

Ethyl 3-(4-hydroxy-2-methylphenyl)propanoate

Lösungsmittel

ethanol

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationThe mixture was filtered through Harborlite
2. 2
   Filtrationfilter aid
3. 3
   Waschenthe pad washed with more ethanol
4. 4
   SonstigeThe combined filtrates were evaporated in vacuo

Vorschrift

A solution of ethyl 3-[4-(benzyloxy)-2-methylphenyl]prop-2-enoate (intermediate 11, 1.054 g) in ethanol (50 ml) was added to a suspension of palladium hydroxide on carbon (0.15 g) in ethanol (5 ml) under nitrogen gas. The resulting suspension was then stirred under a hydrogen atmosphere for 3 hours. The mixture was filtered through Harborlite filter aid and the pad washed with more ethanol. The combined filtrates were evaporated in vacuo to give the title compound as a clear oil.

Quelle