Reaktion #970955

ord-de010a6f56cf47cf92fb2aad06c0cdd6

Reaktionsgleichung

CC(C)(C)OC(=O)N1CCC(N)CC1
1,1-dimethylethyl 4-amino-1-piperidinecarboxylate
N#Cc1ccccc1Br
2-bromobenzonitrile
CC(C)(C)OC(=O)N1CCC(Nc2cccc(C#N)c2)CC1
D5
CC(C)(C)OC(=O)N1CCC(Nc2cccc(C#N)c2)CC1
1,1-Dimethylethyl 4-[(3-cyanophenyl)amino]-1-piperidinecarboxylate
→
CC(C)(C)OC(=O)N1CCC(Nc2ccccc2C#N)CC1
title compound
CC(C)(C)OC(=O)N1CCC(Nc2ccccc2C#N)CC1
1,1-Dimethylethyl 4-[(2-cyanophenyl)amino]-1-piperidinecarboxylate

Edukte

CC(C)(C)OC(=O)N1CCC(N)CC1
1,1-dimethylethyl 4-amino-1-piperidinecarboxylate
N#Cc1ccccc1Br
2-bromobenzonitrile
CC(C)(C)OC(=O)N1CCC(Nc2cccc(C#N)c2)CC1
D5
CC(C)(C)OC(=O)N1CCC(Nc2cccc(C#N)c2)CC1
1,1-Dimethylethyl 4-[(3-cyanophenyl)amino]-1-piperidinecarboxylate

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared from 1,1-dimethylethyl 4-amino-1-piperidinecarboxylate and 2-bromobenzonitrile using a method similar to that described for D5 in Description 5.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08236953B2uspto-grants-2012_08