Reaktion #969908

Reaktionsgleichung

4-(1,4-Diaza-bicyclo[3.2.2]non-4-yl)-phenylamine

benzoyl chloride

→

hydrochloric acid

N-[4-(1,4-Diaza-bicyclo[3.2.2]non-4-yl)-phenyl]-benzamide hydrochloric acid salt

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe mixture was evaporated
2. 2
   Sonstigetriturated with diethyl ether (50 ml)
3. 3
   SonstigeThe crystals were recrystallised from methanol (40 ml)

Vorschrift

4-(1,4-Diaza-bicyclo[3.2.2]non-4-yl)-phenylamine (0.76 g, 3.5 mmol), benzoyl chloride (0.41 g, 3.5 mmol) and dichloromethane (33 ml) was stirred at room temperature for 17 hours. The mixture was evaporated and triturated with diethyl ether (50 ml). The crystals were recrystallised from methanol (40 ml). The hydrochloric acid salt was isolated. Yield 0.54 g (44%). Mp. 260° C. (decomp.).

Quelle