Reaktion #95948

Reaktionsgleichung

N-hydroxyethylethylenediamine

ethylacetoacetate

oleic acid

→

4-oleoyloxyethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.DISTILLATIONAt 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off
2. 2
   Sonstigewas effected at 210° to 215° C.
3. 3
   Sonstigeto distil off 18 g of water

Vorschrift

Into an apparatus similar to that in Example 1, were charged 104.2 g (1 mole) of N-hydroxyethylethylenediamine and 130.1 g (1 mole) of ethylacetoacetate. At 150° to 160° C., 18 g of water and 46 g of ethanol were distilled off. Then, after addition of 282.5 g (1 mole) of oleic acid, the esterification was effected at 210° to 215° C. to distil off 18 g of water and to obtain 4-oleoyloxyethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

Quelle