Reaktion #956705

Reaktionsgleichung

4-methoxy-2-propyl-1H-benzo[d]imidazole

(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile

→

title compound

Ausbeute 54.0%

(E)-2-{3-fluoro-8-[(4-methoxy-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]dibenzo[b,e]oxepin-11(6H)-ylidene}propanenitrile

Ausbeute 54.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained in Reference Example 1

Vorschrift

Using 4-methoxy-2-propyl-1H-benzo[d]imidazole (Journal of Pharmacy and Pharmacology; 1956, vol. 8, p 661, 338 mg, 1.78 mmol) and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (700 mg, 1.95 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, the title compound (448 mg, 54%) was obtained.

Quelle