Reaktion #956702

Reaktionsgleichung

4-methoxy-2-(methoxymethyl)-1H-benzo[d]imidazole

(E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile

→

(E)-2-(3-fluoro-8-{[4-methoxy-2-(methoxymethyl)-1H-benzo[d]imidazol-1-yl]methyl}dibenzo[b,e]oxepin-11(6H)-ylidene)propanenitrile

Ausbeute 53.2%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeobtained in Reference Example 1

Vorschrift

[step 3] Using 4-methoxy-2-(methoxymethyl)-1H-benzo[d]imidazole (1.3 g, 6.8 mmol) obtained in step 2 and (E)-2-[8-(bromomethyl)-3-fluorodibenzo[b,e]oxepin-11(6H)-ylidene]propanenitrile (2.5 g, 7.0 mmol) obtained in Reference Example 1, and in the same manner as in Reference Example 1A, (E)-2-(3-fluoro-8-{[4-methoxy-2-(methoxymethyl)-1H-benzo[d]imidazol-1-yl]methyl}dibenzo[b,e]oxepin-11(6H)-ylidene)propanenitrile (1.7 g, 53%) was obtained.

Quelle