Reaktion #954529

ord-9785e38ceca74e4c83d6aeca79400a0e

Reaktionsgleichung

COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1
COC(=O)C(C)(C)Cc1c(S
C1CCNCC1
C1CCNCC1
→
COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(N2CCCCC2)cc1
COC(=O)C(C)(C)Cc1c(S

Edukte

COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1
COC(=O)C(C)(C)Cc1c(SC(C)(C)C)c
C1CCNCC1
C1CCNCC1

Reagenzien

O=P([O-])([O-])[O-].[K+].[K+].[K+]
O=P([O-])([O-])[O-].[K+].[K+].
[Cu][I]
[Cu][I]
O=C(O)C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1
O=C(O)C(=O)Nc1cc(C(F)(F)F)cc(C

Lösungsmittel

CS(C)=O
CS(C)=O
CS(C)=O
CS(C)=O

Reaktionsbedingungen

Temperatur
80°CELSIUS

Aufarbeitung

  1. 1
    workup.ADDITIONThe reaction vials were then cooled to r.t. and diluted with 100 μL of 5% AcOH in DMSO, containing 1,3,5-trimethoxybenzene (0.005M) and were shaken vigorously.
  2. 2
    workup.ALIQUOT25 microliter of resulting solution is taken
  3. 3
    workup.ADDITIONTo the 25 microliter aliquot 700 microliter of MeCN was added prior to UPLC-MS Analysis

Quelle

DOI: 10.1039/C5SC04751JFigure 4 from Chemistry informer libraries