Reaktion #953784

ord-5bbb0f001d494738af207c37113ac131

Reaktionsgleichung

Clc1ccc2c(c1)CC(N1CCNCC1)c1cc(Cl)ccc1O2
1-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-piperazine
O=C1OCCN1CCCl
3-(2-chloro-ethyl)-2-oxazolidinone
→
Cl.Cl.O=C1OCCN1CCN1CCN(C2Cc3cc(Cl)ccc3Oc3ccc(Cl)cc32)CC1
3-[2-{4-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-1-piperazinyl}-ethyl]-2-oxazolidinone dihydrochloride

Edukte

Clc1ccc2c(c1)CC(N1CCNCC1)c1cc(Cl)ccc1O2
1-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-piperazine
O=C1OCCN1CCCl
3-(2-chloro-ethyl)-2-oxazolidinone

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

1-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-piperazine is reacted with 3-(2-chloro-ethyl)-2-oxazolidinone in the manner described in Example 1, and there is obtained 3-[2-{4-[2,8-dichloro-10,11-dihydro-dibenz[b,f]oxepin-10-yl]-1-piperazinyl}-ethyl]-2-oxazolidinone dihydrochloride having a melting point of 187°-188° C (with decomposition).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04100173uspto-grants-1978_07