Reaktion #95250

Reaktionsgleichung

2-(5-carboxypentyl)-2-cyclopentenone

p-toluenesulfonic acid

→

2-(5-carbethoxypentyl)-2-cyclopentenone

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent is evaporated
2. 2
   workup.DISSOLUTIONthe residue is dissolved in ether
3. 3
   WaschenThe organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution
4. 4
   Trocknendried (MgSO4)
5. 5
   Sonstigeevaporated
6. 6
   Sonstigeto give 1.371 g

Vorschrift

A solution of 1.309 g. (0.00668 mole) of 2-(5-carboxypentyl)-2-cyclopentenone (Example 52) and 90 mg. of p-toluenesulfonic acid in 150 ml. of ethanol is refluxed for 18 hours. The solvent is evaporated and the residue is dissolved in ether. The organic phase is washed with water, sodium bicarbonate solution, and saturated saline solution, dried (MgSO4), and evaporated to give 1.371 g. of a light yellow oil.

Quelle